Grape Seed

Price:
8.95 USD
Was:
11.19 USD
Size:
25
Grams
50
Grams
100
Grams
250
Grams
500
Grams
1
KG

Biotanica, Grape Seed, Premium PCO Phytosome Extract
  • Assists Cell Production*
  • Cardiovascular Health*
  • Improves Metabolism*
  • Assists Natural Healing*


Soy Free

Cruelty Free

Egg Free

Wheat Free

Dairy Free

Meat Free

100% Natural

Gluten Free

NZ Packed

Recyclable
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8.95 USD

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Soy Free

Cruelty Free

Egg Free

Wheat Free

Dairy Free

Meat Free

100% Natural

Gluten Free

NZ Packed

Recyclable
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Soy Free

Cruelty Free

Egg Free

Wheat Free

Dairy Free

Meat Free

100% Natural

Gluten Free

NZ Packed

Recyclable
Low Price Guarantee
Found a lower price?
We'll beat it.
Fast, Free Shipping *
Orders shipped within
2 business days.
Free ship over 79 USD
Customer Support
Ambassadors standing
by 7 days a week.
90 Day Returns
Money back options! Don't
like it? Simply send it back!

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Product Description
Grape Seed Extract is a product derived from the seeds of red wine grapes.  

Our Grape seed extract is extremely rich in antioxidants (oligomeric proanthocyanidin complexes). The extract has been used for a long time touting many health benefits including supporting health oxidation, infection symptoms, and healthy bowel movements.Although the extract is well known, it is still fairly new to nations like the U.S. *
Product Benefits
In addition to the many traditional benefits that Grape Seed Extract is believed to have, studies have been conducted to clearly determine the various benefits this super extract contains. We will introduce you to the benefits and the reasoning behind consuming the Grape Seed 95% Extract including supporting health blood pressure, cognitive function, inflammation, healthy immune system and gut health. *
  • Healthy Blood Pressure. Grape Seed extract has the ability to support healthy blood pressure. A study conducted on humans with an above average vascular risk showed that intake of Grape Seed extract contributed to the improvement of flow-mediated dilation [8]. This was by a margin of 1.1% on the control group. The extract was also discovered to support blood pressure in individuals with metabolic syndrome. Our extract is rich in antioxidants (such as linoleic acid, phenolic procyanidins and flavonoids) that will help to protect your blood vessels from damage [8][9]. This, in turn, will help support healthy blood pressure.
  • The extract has also been found to help with the dilation of blood vessels. Pre-hypertensive individuals also showed an improvement in their blood pressure after consuming the extract. This suggests that this super extract can help to support healthy blood pressure.*
  • Cognitive Function. Grape Seed extract has been found to support brain amyloid cells [5]. This improves our cognition and is also linked to a healthy memory and recall in rats. The study was conducted on female rats and it further shoed that the extract was able to support healthy glucose levels, hydrogen peroxide and cellular damage. In turn, the extract will increase the level of good compounds such as the sulfhydryl content in the hippocampus [5]. The cognitive ability of the rats was also greatly boosted. This shows that the extract will also help support cognitive function as we age [5].
  • In the occurrence of high nitric oxide (NO), the extract was able to protect the astroglial cells. These are cells found in our glutathione reserves and are normally protected against H2O2- mediated damage.*
  • Health Cell Replication. Grape Seeds contain proanthocyanidins, an important compound in the the support of healthy cell replication [6]. A study published in Molecular Nutrition & Food Research discovered that Grape Seeds can support the health of skin cells. This study involved the use of hairless mice to test the ability of Grape Seed proanthocyanidins in slowing down the formation of healthy cell masses on the skin. The conclusion reached was that Grape Seed extracts could be useful in the attenuation of UV-induced health effects on human skin [3].
  • Studies conducted on cells indicated that the Grape Seed extract was able to assist in the management of healthy cell replication. The extract was also able to aid in the apoptosis (death of cells) to furtner support cell health. Another study that involved head and neck squamous cell carcinomas deduced that the use of the extract aided in the management of damaged DNA and induced cell death to maintain healthy cell health [3][4].*
  • Flammation Homeostasis. Studies conducted to determine the presence of pro-calming properties in grape Seed extract discovered that this extract potently provide a pro-calming response in LPS-stimulated macrophages [2][6]. Another study was conducted with rats on a high-fat diet. Grape Seed extract helped manage their blood sugar levels and also improved pro-calming markers in white fat tissue.
  • In human macrophages stimulated by LPS, our extract was found to support a pro-calming response [2]. In astrocytes, the levels of beneficial cytokines were increased after intake of the extract. When neural cells were challenged with H2O2, the extract prompted a pro-calming response [1][2].*
  • Stomach Health. A rat model with IBS was fed with Grape Seed extract and it was discovered that stomach health were greatly improved after a certain period [7]. Grape Seed extract was also able to protect and improve the condition of the intestines in terms of goblet cell density and the decrease of claudin 2. The extract was able to support a healthy gut flora in rats with IBS. It was also able to support a healthy bacteroid count in both samples of diseased and healthy rats [7]. Lactobacilli count was also restored.
  • At lower doses, this super extract was found to effectively support stomach health in people with stomach ulcers [1]. Intestinal tight junction proteins also showed improvement as a result of this extract. The fecal levels of calprotectin (a marker of intestinal challenges) were also well supported.*
Suggested Use
The recommended dosage for this extract is 100 - 300 mg daily.
Interactions & Warnings
Grape Seed extract may sometimes act as an anticoagulant. The University of Maryland Medical Center conducted a study which discovered that the extract can act as a blood thinner. Therefore, there is a high chance of increased bleeding if taken in combination with blood-thinners such as warfa**n or aspirin. Pregnant women should also avoid the use of this extract as studies on it have yet to be completed.Always consult with your doctor or health professional before changing your health regime.
Shelf Life
2 Years from Date of Manufacture.
Storage
Use a sealed container to store this product in a cool, dry place. Keep away from direct light and moisture. Once the package is opened, it must be re-sealed and used within 6 months.
References
  1. Saito, M., Hosoyama, H., Ariga, T., Kataoka, S., & Yamaji, N. (1998). Antiulcer activity of grape seed extract and procyanidins. Journal of Agricultural and Food Chemistry, 46(4), 1460-1464.
  2. Jayaprakasha, G. K., Singh, R. P., & Sakariah, K. K. (2001). Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro. Food chemistry, 73(3), 285-290.
  3. Kaur, M., Agarwal, C., & Agarwal, R. (2009). Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products. The Journal of nutrition, 139(9), 1806S-1812S.
  4. Kaur, M., Singh, R. P., Gu, M., Agarwal, R., & Agarwal, C. (2006). Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells. Clinical Cancer Research, 12(20), 6194-6202.
  5. Wang, J., Ho, L., Zhao, W., Ono, K., Rosensweig, C., Chen, L., ... & Pasinetti, G. M. (2008). Grape-derived polyphenolics prevent oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease. Journal of Neuroscience, 28(25), 6388-6392.
  6. Devi, S. A., Chandrasekar, B. S., Manjula, K., & Ishii, N. (2011). Grape seed proanthocyanidin lowers brain oxidative stress in adult and middle-aged rats. Experimental gerontology, 46(11), 958-964.
  7. Yazbeck, R., & Howarth, G. S. (2009). Complementary medicines: emerging therapies for intestinal mucositis. Cancer biology & therapy, 8(17), 1629-1631.
  8. Sivaprakasapillai, B., Edirisinghe, I., Randolph, J., Steinberg, F., & Kappagoda, T. (2009). Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome. Metabolism, 58(12), 1743-1746.
Disclaimer
While Biotanica® strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by Biotanica® or any other health advice, information or independent product reviews.
Supplement Facts
Serving Size:
TAKE 100 - 300mg DAILY.
Amount Per Serving
% Daily Value
GRAPE SEED 95% PCO STANDARDIZED EXTRACT.
100 mg
**
** Daily value not established.
Customer Reviews
4.25
12
5 Stars
50%
(6)
4 Stars
25%
(3)
3 Stars
25%
(3)
2 Stars
0%
(0)
1 Star
0%
(0)
Disclaimer: Product reviews solely reflect the views and opinions expressed by the contributors and not those of Biotanica®


Biotanica® Customer
The Best
Posted by Biotanica® Customer on August 28 2018 | Verified Purchase
Very good
Biotanica® Customer
Very helpful product
Posted by Biotanica® Customer on August 26 2018 | Verified Purchase
Great quality and price! My go to!
Yasmine
Not suitable for me
Posted by Yasmine on August 16 2018 | Verified Purchase
Did not make a difference
Adrienne S.
Love
Posted by Adrienne S. on July 16 2018 | Verified Purchase
Great quality and price! My go to!
Zackary M.
ADD
Posted by Zackary M. on June 22 2018 | Verified Purchase
Has helped my son's ADD.
Biotanica® Customer
Amazing
Posted by Biotanica® Customer on April 15 2018 | Verified Purchase
Working well for me and am thankful.
Biotanica® Customer
Helped my candida
Posted by Biotanica® Customer on March 19 2018 | Verified Purchase
Used for two months to help control my candida. Really noticed a difference.
Biotanica® Customer
Good product good price
Posted by Biotanica® Customer on March 14 2018 | Verified Purchase
Very helpful product
Biotanica® Customer
Ok
Posted by Biotanica® Customer on February 20 2018 | Verified Purchase
Been using for two weeks but seen no change yet
Luka
Great antioxidant!
Posted by Luka on February 19 2018 | Verified Purchase
Cheap price and potent antioxidant.
Dominique
Slow Delivery
Posted by Dominique on January 18 2018 | Verified Purchase
Been using for two weeks but seen no change yet
Biotanica® Customer
Amazing
Posted by Biotanica® Customer on January 01 2018 | Verified Purchase
Better then expected




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